Accelerating drug discovery through structural biology

HarkerBIO is a diverse research services provider within the structural biology, drug discovery, and protein development arena. We are happy to help you with any research needs that focus on proteins - be it structural studies, optimization, or discovery.

Our areas of expertise include therapeutics discovery (small molecules or biologics), protein design and optimization, natural diversity exploration, custom proteins, biochemistry, assay development, and other related disciplines.

Our Structural Biology Services

We are immediately available to provide you with the highest level of service with rapid turn-around at a very reasonable cost. Our expertise in structural biology and protein optimization is at your disposal - we can help you accomplish your research objectives and drive your projects forward. We expedite your work through the application of our deep expertise in structural biology, drug discovery, and protein design/optimization. Additionally we offer help with screening natural biodiversity of proteins, the design and discovery of custom proteins, biochemistry/biophysics, assay design, and scientific consulting.

Partnerships to Accelerate Progress

We have a proven track record of successful R&D partnerships with both industry and academia and our scientific team has decades of experience in handling tough protein targets. Teaming with HarkerBIO will engage our highly trained and experienced scientists and state-of-the-art infrastructure in support of your organization's R&D projects.

Through our high-throughput pipeline pharmaceutical and biotechnology companies, start-ups, or academic labs can gain access to the cutting edge technologies in Structural Biology and Protein Design. Our gene-to-structure pipeline integrates technologies developed at the world-renowned Hauptman-Woodward Medical Research Institute (HWI), as well as state of the art processes and know-how based on decades of scientific experience. The HarkerBIO pipeline is a clear path from your idea to an atomic resolution three-dimensional structure of your target (or target-drug complex), which greatly accelerates the drug design or protein design process.

Protein Design and Crystallography

X-ray crystal structures provide atomic-level details of the function of proteins and an unparalleled level of insight into the protein-drug complexes - ideal for rapid optimization of drug-like small molecules. Structural information is key to successful protein optimization, production, and design - it is well established that the success of protein design is directly proportional to the amount of structural information known for the target. We are happy to help you optimize your protein of interest, or to work with you on the design and discovery of novel proteins to fit your specific needs. X-ray structures are also key components of successful IP strategy, scientific publications, and they provide unique imagery used in effective marketing of scientific products.

Together, we can accelerate your R&D projects!

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Monthly Crystallization Screening